Effect of Dry Hydrogen Peroxide on Candida Auris Environmental Contamination¹

Published September 2023 in Antimicrobial Stewardship & Healthcare Epidemiology.

Candida auris is an emerging pathogen that exhibits broad antimicrobial resistance and causes highly morbid infections. Prolonged survival on surfaces has been demonstrated, and standard disinfectants may not achieve adequate disinfection. Persistent patient colonization and constant environmental recontamination poses an infection risk that may be mitigated by no touch disinfection systems. We evaluated the efficacy of continuous dry hydrogen peroxide (DHP) exposure on C. auris environmental contamination.

Impact of Dry Hydrogen Peroxide on Environmental Bioburden Reduction in a Long-Term Care Facility²

Published June 2023 in American Journal of Infection Control.

Environmental infection transmission is a perennial problem in long-term care facilities (LTCFs), exacerbated by shared living arrangements, residents with cognitive deficits, staffing shortages, and suboptimal cleaning and disinfection. This study evaluates the impact of dry hydrogen peroxide (DHP), as a supplement to manual decontamination, on bioburden within an LTCF neurobehavioral unit.

Impact of Dry Hydrogen Peroxide on Hospital-Acquired Infection at a Pediatric Oncology Hospital³

Published December 2021 in American Journal of Infection Control.

This study aims to describe the effect of DHP, as an adjunct to environmental cleaning and disinfection, on the incidence of hospital-acquired infections (HAIs) at Unidad Nacional de Oncologia Pediatrica (UNOP) in Guatemala City, Guatemala.

Treatment with Dry Hydrogen Peroxide Accelerates the Decay of Severe Acute Syndrome Coronavirus-2 on Non-porous Hard Surfaces⁴

Published July 2021 in American Journal of Infection Control.

Disinfection of contaminated or potentially contaminated surfaces has become an integral part of the mitigation strategies for controlling coronavirus disease 2019. In this study, the feasibility of using DHP™ in inactivating SARS-CoV-2 on contaminated surfaces in large indoor spaces was evaluated.

An Effective and Automated Approach for Reducing Infection Risk from Contaminated Privacy Curtains⁵

Published June 2021 in American Journal of Infection Control.

There is limited information on how to reduce levels of curtain contamination while they are in use and between changings. Here we describe the outcome of using DHP to reduce levels of contamination on privacy curtains used in different areas of the hospital.

Evaluation of Dry Hydrogen Peroxide in Reducing Microbial Bioburden in a Healthcare Facility⁶

Published March 2021 in American Journal of Infection Control.

Standard manual cleaning and disinfection practices are often inadequate. Persistent contamination in the environment poses an infection risk that may be mitigated by no-touch disinfection systems.  This study evaluates the efficacy of DHP on microbial air and surface contamination as an adjunct to routine cleaning and disinfection in a large urban hospital.

Effectiveness of Dry Hydrogen Peroxide on Reducing Environmental Microbial Bioburden Risk in a Pediatric Oncology Intensive Care Unit⁷

E-published August 2020 in American Journal of Infection Control.

Routine manual cleaning and disinfection of the health care environment is often suboptimal. Residual contamination poses an infection risk, particularly for immunocompromised patients. This study evaluates the efficacy of dry hydrogen peroxide DHP on microbial surface contamination in a pediatric oncology intensive care unit.

Dilute Hydrogen Peroxide Technology for Reduction of Microbial Colonization in the Hospital Setting⁸

Published June 2015 in American Journal of Infection Control.

It is estimated that hospital-acquired infections (HAIs) cost US hospitals over $30 billion annually. Dilute hydrogen peroxide (DHP) technology is a new patented technology that utilizes ambient air to produce hydrogen peroxide as a near-ideal gas, creating concentrations of peroxide that are well below the Environmental Protection Agency safety thresholds. In laboratory testing, DHP has demonstrated potent disinfective activity against a variety of bacteria, fungi, and viruses.

References: 1. Jennifer Sanguinet, Gerard Marchall, Julia Moody, and Kenneth Sands, Effect of dry hydrogen peroxide on Candida auris environmental contamination. Cambridge University Press. 2023 September. https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology/article/effect-of-dry-hydrogen-peroxide-on-candida-auris-environmental-contamination/ED82D581233B948EF82392450FB73EF3 2. Cole, Mary, Impact of dry hydrogen peroxide on environmental bioburden reduction in a long-term care facility. Am J Infect Control. 2023 June. https://doi.org/10.1016/j.ajic.2023.06.004 3. Melgar M, Ramirez M, Chang A, Antillon F. Impact of dry hydrogen peroxide on hospital-acquired infection at a pediatric oncology hospital [published online ahead of print, 2021 Dec 29]. Am J Infect Control. 2021;S0196-6553(21)00851-8. https://doi:10.1016/j.ajic.2021.12.010 4. Huang YS, Bilyeu AN, Hsu WW, et al. Treatment with dry hydrogen peroxide accelerates the decay of severe acute syndrome coronavirus-2 on non-porous hard surfaces. Am J Infect Control. 2021;49(10):1252-1255. https://doi:10.1016/j.ajic.2021.07.006 5. Sanguinet J, Lee C. An effective and automated approach for reducing infection risk from contaminated privacy curtains. Am J Infect Control. 2021;49(10):1337-1338. https://doi:10.1016/j.ajic.2021.06.004 6. Sanguinet J, Edmiston C. Evaluation of dry hydrogen peroxide in reducing microbial bioburden in a healthcare facility. Am J Infect Control. 2021;49(8):985-990. https://doi:10.1016/j.ajic.2021.03.004  7. Ramirez M, Matheu L, Gomez M, et al. Effectiveness of dry hydrogen peroxide on reducing environmental microbial bioburden risk in a pediatric oncology intensive care unit. Am J Infect Control. 2021;49(5):608-613. Epub 2020 Aug 20. https://doi:10.1016/j.ajic.2020.08.026 8. Herman CK, Hess J, Cerra C. Dilute hydrogen peroxide technology for reduction of microbial colonization in the hospital setting. Abstract only. Am J Infect Control. 2015;43(6):S25-S26. https://doi.org/10.1016/j.ajic.2015.04.064.