Our remedy designed for defeating pathogens.
Introducing the New Standard of Care With the Synexis BioDefense System.
Infections caused by microbes like viruses and bacteria have always posed a major threat to healthcare systems. An estimated 99,000 patients die each year from healthcare-associated infections (HAIs)1, and it can cost hospitals anywhere between $28 billion and $45 billion.2
But Synexis can redefine how healthcare systems seek the reduction of microbes both in the air and on surfaces. Our DHP™ (Dry Hydrogen Peroxide) producing biodefense system continuously attacks viruses, bacteria, and odors along each step of the patient’s journey, from hectic ERs to outpatient clinics.
Our impressive DHP technology.
Synexis is the sole developer of the process by which naturally occurring oxygen and humidity are taken from the air to create Dry Hydrogen Peroxide (H2O2), otherwise known as DHP.
In the air and on surfaces: Where DHP flows.
Chasing Zero: Mitigating Microbes at a Medical Center
A 762-bed acute care facility in Las Vegas, NV faced challenges around effective cleaning habits in constantly re-contaminated environments. Unfortunately, it’s not a unique challenge.
That’s what prompted Dr. Jennifer Sanguinet, DrPH, Principal Investigator, to speak with Synexis founder Jim Lee about DHP Technology. Sunrise Hospital implemented Synexis in five of their units, and kept a scientific eye on the results. Read below about some of the impressive changes that were seen.
"DHP significantly reduces the organisms in the air and on surfaces. The reduction promotes a cleaner environment which can reduce the risk of a hospital-acquired infection. DHP can help us continue chasing zero."
Clinical Study Published in American Journal of Infection Control: Evaluation of DHP in Reducing Microbial Bioburden in a Healthcare Facility⁴
Sunrise Hospital, a 762-bed acute care facility in Las Vegas, NV, conducted a study evaluating the efficacy of DHP Technology on microbial air and surface contamination as an adjunct to routine cleaning and disinfection. Published in AJIC, the powerful results tell the tale all themselves.
DHP demonstrated a statistically significant 96.5% reduction in the average number of bacteria collected in all surface environmental samples after one day (p < .001). The greatest reduction was seen on soft surfaces (like notoriously hard-to-clean privacy curtains) where DHP demonstrated a 99.5% reduction after one day. Explore more results from this extensive study below.
Effectiveness of DHP on Reducing Environmental Microbial Bioburden Risk in a Pediatric Oncology Intensive Care Unit
By analyzing surface samples from rooms in the intensive care unit before and after DHP was deployed, this study demonstrates that the overall mean surface microbial burden was significantly reduced.
Simply put, DHP was proven effective and improved the quality of environmental cleaning. Read more about the results.
DHP Technology for Reduction of Microbial Colonization in the Hospital Setting
In this study, DHP was incorporated into a community hospital’s 34-bed Cardiovascular/Telemetry unit’s existing HVAC system. The study was designed to answer the question: Does DHP reduce microbial contamination in the hospital unit?
The results showed a significant reduction in microbes over seven days. Dig into the details below.
Clinical Study Published in American Journal of Infection Control: An Effective and Automated Approach for Reducing Infection Risk From Contaminated Privacy Curtains⁵
Privacy curtains are widely used in hospitals and healthcare spaces. Frequently touched by both providers and patients, they easily become contaminated—and are only as clean as the last time they were manually cleaned. Plus, they’re generally only changed out twice a year.
A study in AJIC describes the successful reduction of curtain contamination in five different units using continuous DHP technology. Results showed that the microbial load was reduced by 99.47% on Day 1. Read more about how the statistically significant reductions were maintained throughout the 28-day study.
Infection Specialists and Pharmacists Share Responsibility for Ensuring Patient Safety⁶
The United States Pharmacopeia (USP) has identified collaboration between infection preventionists and pharmacists as a necessary component of successful compliance with USP General Chapter <797>, the foundation of which is to prevent patient harm from microbial contamination.
Dramatic advancements in environmental technologies have helped mitigate the inadequacy of manual cleaning and disinfection. A case report from an inpatient hospital in Indiana determined that DHP technology continuously helps address active shedding and contamination in real time without disrupting pharmacy workflow, enabling successful compliance with USP <797>. Read about how they overcame their challenges with DHP technology below.
Dry Hydrogen Peroxide: A Novel Solution for Reducing Microbial Bioburden in Healthcare
Healthcare-associated infections (HAIs), and now COVID-19, place a huge burden on the U.S. healthcare system and the patients it serves. Research has revealed that even after manual cleaning, as many as 50% of surfaces remain contaminated with pathogens, including multi-drug resistant organisms (MDROs).⁷
Now, an innovative technology has emerged to support the efforts expended on environmental cleaning and disinfection—Synexis and its unique DHP Technology. Read about reducing microbial bioburden in the healthcare setting below.
Spread the Word
Read our brochure, pass it around, and share how Synexis can help make your healthcare facility a cleaner place.
References: 1. Arnold C. “Rethinking sterile: the hospital microbiome,” Environmental Health Perspectives, 2014. 2. Stone P. W. “Economic burden of healthcare-associated infections: an American perspective,” Expert Rev Pharmacoecon Outcomes Res, 2009. 3. “Hydrogen Peroxide,” Occupational Safety and Health Administration, 2018, www.osha.gov/chemicaldata/chemResult.html?recNo=630 4. Sanguinet J, Edminston C. Evaluation of Dry Hydrogen Peroxide in Reducing Microbial Bioburden in a Healthcare Facility. American Journal of Infection Control. 2021 Mar; DOI: https://doi.org/10.1016/j.ajic.2021.03.004 5. Sanguinet J, Lee C. An effective and automated approach for reducing infection risk from contaminated privacy curtains. American Journal of Infection Control. 2021 June; DOI:https://doi.org/10.1016/j.ajic.2021.06.004 6. Kaiser, C., & Roe, A. (2020, November 23). Infection Specialists and Pharmacists Share Responsibility for Ensuring Patient Safety. Pharmacy Times, 9(6). 7. Chemaly RF, Simmons S, Dale C et al. The role of the healthcare environment in the spread of multidrug-resistant organisms: update on current best practices for containment. Ther Adv Infect Dis. 2014 Jun;2(3- 4):79-90. https://www.ncbi.nlm.nih.gov/pubmed/25469234